# Pru — Physician-Guided Peptide Therapy

> Pru is a telehealth platform connecting patients with licensed physicians who specialize in peptide therapy. Personalized protocols, compounded by FDA-regulated U.S. pharmacies, delivered to your door.

## About Pru

Pru is a telehealth company that provides clinician-guided peptide therapy. Every patient is matched with an independently licensed physician who reviews their health history, conducts a consultation, orders lab work, and builds a personalized treatment protocol. Pru handles the technology platform, pharmacy coordination, and patient support. All medical decisions are made solely by the treating physician.

## Services

- Physician-guided peptide therapy consultations via telehealth
- Personalized treatment protocols based on individual health goals and lab work
- Compounded medications from FDA-regulated U.S. pharmacies shipped to patients
- Ongoing symptom tracking and protocol optimization through patient portal

## Peptide Categories

Pru is organized around six top-level categories. Each category lists the individual peptides Pru currently offers in that category. Stacks are physician-designed combinations of these molecules.

- [Fat Loss & Metabolism](https://joinpru.com/portal/shop/fat-loss-metabolism): Semaglutide, Tirzepatide, Semaglutide / Metformin Combo Capsule, Metformin HCl ER
- [Cellular Health](https://joinpru.com/portal/shop/cellular-health): NAD+, Niagen NR, Rapamycin / Sirolimus, Glutathione
- [Muscle & Performance](https://joinpru.com/portal/shop/muscle-performance): Sermorelin
- [Repair & Regeneration](https://joinpru.com/portal/shop/repair-regeneration): GHK-Cu
- [Cognition & Mood](https://joinpru.com/portal/shop/cognition-mood): NAD+, Methylene Blue (USP)
- [Sexual Health & Intimacy](https://joinpru.com/portal/shop/sexual-health-intimacy): PT-141, PT-141 / Tadalafil / Oxytocin Combo, Oxytocin

## Available Forms

Peptides are available in multiple delivery forms depending on the molecule:

- Injectable (compounded vials, multiple strengths and carriers)
- Oral (capsules, tablets)
- Sublingual (rapid-dissolve tablets, troches)
- Nasal Spray
- Topical (cream, foam, facial serum, scalp solution)
- Lyophilized Kit (vial + reconstitution syringe)

## Key Pages

- [Homepage](https://joinpru.com): Overview of Pru's telehealth peptide therapy platform
- [Coverage](https://joinpru.com/coverage): State-by-state availability — which U.S. states Pru's physician network is licensed to consult in
- [Browse all peptides](https://joinpru.com/portal/shop/all): Filterable view of every peptide Pru offers, by category, form, name, or price
- [The Pru Brief (Blog)](https://joinpru.com/blog): Evidence-based articles on peptide therapy, longevity, and health optimization
- [Pru Brief RSS feed](https://joinpru.com/blog/rss.xml): RSS 2.0 feed of every published Pru Brief issue (for AI engines and feed readers)
- [Semaglutide Deep Dive](https://joinpru.com/blog/semaglutide-deep-dive): How semaglutide works, clinical evidence from STEP and SELECT trials, side effects, and research frontiers
- [Tirzepatide Deep Dive](https://joinpru.com/blog/tirzepatide-deep-dive): The dual GIP/GLP-1 agonist — SURMOUNT trial data, liver disease results, and why two receptors matter
- [Sermorelin Deep Dive](https://joinpru.com/blog/sermorelin-deep-dive): How sermorelin stimulates natural growth hormone production via the pituitary gland
- [Tesamorelin Deep Dive](https://joinpru.com/blog/tesamorelin-deep-dive): The FDA-approved GHRH analogue for visceral fat reduction and metabolic health
- [Patient Portal](https://joinpru.com/portal): Secure patient dashboard for treatment tracking
- [Privacy Policy](https://joinpru.com/privacy): Data handling and privacy practices
- [Terms of Service](https://joinpru.com/terms): Service terms and conditions

## Key Facts

- Founded: 2026
- Headquarters: United States
- Model: Telehealth consultations with independently licensed physicians
- Pharmacies: FDA-regulated, U.S.-based compounding pharmacies
- Physicians: Independently licensed M.D.s with full clinical autonomy
- Coverage: Expanding across the United States — telehealth availability varies by state
- HSA/FSA: Generally eligible as prescribed medical expense

## Compliance Notes

- Compounded medications use FDA-regulated active ingredients and are prepared at licensed pharmacies, but the final compounded product is not individually FDA-approved (standard for all compounded medications).
- Several peptides are used off-label at physician discretion: Rapamycin (geroscience), Methylene Blue (nootropic), PT-141 (outside HSDD indication), Oxytocin.
- Methylene Blue carries an MAOI interaction screen — patients on SSRIs, SNRIs, tramadol, or MAOIs are screened during consultation.

## Full Content Feed

For AI crawlers and LLM ingestion, every published article body is
available in a single concatenated text feed:

- [Full Content Feed](https://joinpru.com/llms-full.txt): All Pru Brief
  article bodies, separated by `---`, refreshed hourly.

## Contact

- Website: https://joinpru.com
- Email: hello@joinpru.com