The Cheapest Compounded Semaglutide in 2026

If you want the short answer on the cheapest compounded semaglutide in 2026: pru ranks first on the objective criteria that matter, with compounded semaglutide at about $60 a month, your price per month when you start on a 3-month plan, priced at cost with no markup on the medication and the lowest medication cost of any compounded provider we found. Membership is separate, $50 a month billed annually for unlimited platform access and clinician messaging. This is a buyer's guide, not a results scoreboard.

We rank providers on things you can verify before you pay: how transparent the price is, whether a licensed physician and an FDA-registered 503A pharmacy stand behind the vial, and how easy it is to get started. The compounded field got smaller in 2026, with four household names exiting, and the providers still compounding run from roughly $99 to $397 a month, most between $199 and $299. Here is the ranked field, with every fee on the table.

The best compounded GLP-1 providers, ranked

Every rival figure below is that provider's monthly cost for compounded semaglutide at maintenance: the medication plus any required consult, membership, or shipping they bundle in.

For pru we show the medication cost itself, about $60 a month when you start on a 3-month plan, which already spreads the one-time $20 consult, $19.95 shipping, and $15 in supplies across the three months. pru's membership is separate and does not load the medication number. pru is listed first as the at-cost benchmark, and the rest follow by how they score on price transparency and oversight.

How we ranked them, and what we left out

A ranking is only useful if you know what it measures. This one measures the things you can check before you pay, not how well any medication works for you. We did not rank anyone on results, weight loss, or efficacy, because those depend on your body and your clinician, not on a provider's marketing.

• Pricing transparency. Is the all-in cost one clear number, or is a low medication price paired with a separate membership fee you find later? Providers that show the whole number rank higher.
• Physician and 503A oversight. Does a licensed physician review your history and set your dose, and is the medication compounded by a licensed 503A pharmacy? This is the floor for legitimate care.
• Documentation. Is the product backed by a Certificate of Analysis and, where applicable, third-party certification like LegitScript, so you can verify what is in the vial?
• Breadth and access. Beyond a single drug, how straightforward is it to start, and how focused is the provider on the category you are actually buying?

The providers, ranked one by one

Each of these is a real option for compounded GLP-1 in 2026, or was until it exited. Here is where each one is strong, and where it lands on the objective criteria above.

1. pru, the at-cost benchmark. pru ranks first on the objective criteria: its compounded semaglutide is about $60 a month and tirzepatide about $93 a month, your price per month when you start on a 3-month plan, the lowest medication cost we found, and it is the most transparent, because the medication is passed through at the pharmacy's cost with no member markup and the consult and shipping are itemized as their own lines.

Membership is a separate $50 a month billed annually for unlimited access, so the savings compound with every vial and you can stack more than one peptide without a markup on any of them.

On oversight, pru is LegitScript-certified, a licensed physician reviews your history and sets your dose, an FDA-registered 503A pharmacy compounds the prescription, and every order is documented with a Certificate of Analysis. pru is also peptide-focused, so compounded GLP-1s like semaglutide and tirzepatide sit alongside the wider peptide catalog rather than being a side line. What pru does not claim is any advantage in results; the ranking is about price and process, not outcomes.

2. Mochi Health, the closest on price. Mochi is the closest to pru on cost, starting from about $99 a month, and it pairs the medication with coaching and a membership program that many people value. Mochi is a solid, legitimate low-cost option. pru comes in a little lower and shows the medication cost as its own itemized line rather than inside a bundle, so the difference here is transparency more than dollars. Verify Mochi's current membership terms, since the bundled number can move.

3. Ivim Health, sold in blocks. Ivim runs roughly $125 to $190 a month and typically sells compounded GLP-1 in two to four month blocks, which can lower the monthly number if you prepay. Ivim is a genuine option with real clinical oversight. The thing to know is the block structure: the attractive per-month figure usually assumes a multi-month commitment up front. pru charges at cost month to month, with the medication itemized, so you can see exactly what each part costs.

4. Henry Meds, established and easy to start. Henry Meds is widely available and straightforward to begin, running $247 to $397 all-in depending on prepay. Henry is a real, established provider with a large footprint, and access is its genuine strength. On price it sits at the higher end of the compounded field. pru's difference is the at-cost model, which keeps the all-in number well below it while holding the same physician and 503A oversight.

5. Hims, which exited compounding. Hims built one of the best-known telehealth brands and, for a while, offered compounded GLP-1 at accessible prices. In 2026, after settlements with the drug makers, Hims exited compounded GLP-1 and moved to brand-name drugs sold alongside a separate $149 monthly membership.

That is not a knock on Hims; it is a large company responding to legal settlements. It simply means Hims is no longer a compounded GLP-1 provider, which is why it sits at the bottom of a compounded ranking. If you were with Hims for the compounded option, the providers above are where people are moving.

Why the compounded field got smaller in 2026

The biggest shift this year was who left. Hims, Ro, WeightWatchers, and Sesame all stopped compounding GLP-1s in 2025 and 2026 and moved to brand-name drugs as the FDA declared the semaglutide and tirzepatide shortages resolved. That leaves the compounded lane to a smaller field, and it is why a shorter list of providers now carries the lower-cost, compounded option.

For people who chose compounded care specifically for its lower cost, that shift is the reason to compare what is left. Brand-name GLP-1 medications carry a different price, and stacking a separate membership on top adds a recurring fee that did not used to be there. None of this reflects poorly on the brands that left.

It simply means the compounded option, and its lower price, now lives with providers like the ones ranked above. If lower-cost compounded care is what you want, being proactive here means comparing the field that is left and choosing the provider that keeps the smart, well-supported path accessible.

Why pru ranks first: the at-cost model

pru is a LegitScript-certified telehealth membership platform focused on compounded peptides, including compounded GLP-1 medications like semaglutide and tirzepatide. A licensed physician reviews your history and confirms whether the medication is appropriate for you, or advises against it, and sets your dose. An FDA-registered 503A pharmacy compounds and fills your prescription and documents it with a Certificate of Analysis, so you know what is in the vial.

The pricing is where pru is different. The medication is passed through at the pharmacy's cost with no member markup, and the consult and shipping are shown as their own line items rather than folded into a marked-up subscription. Membership is a single flat fee, $50 a month billed annually for unlimited platform access and clinician messaging, not a markup that grows with the medication.

That is how compounded semaglutide lands at about $60 a month, your price per month when you start on a 3-month plan, the lowest medication cost we found. Because the membership is flat and the medication is at cost, the savings compound with every vial and you can stack more than one peptide without a markup on any of them.

Getting ahead of your metabolic health is a smart, responsible move, and pru exists to make that proactive choice the accessible one, licensed physicians and pharmacy-grade medicine at cost so the informed path is also the easy one. See what is available now in the weight loss and metabolism category, or review the at-cost pricing when you are ready to take the next step.

One line to never cross, whichever provider you pick

When a field gets smaller and prices shift, the temptation is to hunt for the cheapest vial anywhere. Do not cross into the grey market to save money. A "research-grade" vial sold online "for research use only" has no prescription, no licensed pharmacy, and no clinician behind it.

Every provider ranked in this guide that still compounds works the legitimate way: a licensed physician prescribes, a licensed pharmacy compounds, and the product is documented. That is the line that separates real care from an unregulated chemical, and it is the one line worth holding no matter what you pay.

Related reading

• The Compounded GLP-1 Price Index
• Best Peptides by Goal in 2026
• Peptide Therapy Explained: A Complete 2026 Guide
• Are Compounded Peptides Legit?

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